Guanidine hydrochloride

Guanidine hydrochloride HN=C(NH2)2•HCL

Structural formula: HN=C(NH2)2•HCL

Molecular formula: CH5N3•HCL

Molecular weight: 95.54

Standard: Industrial grade and Medicine grade

Uses: 1. Used as an intermediate for medicines, pesticides, dyes and other organic compounds. It is an important raw material for the manufacture of sulfonamides and folic acid. It can also be used as an antistatic agent for synthetic fibers. It is an important raw material for sulfadiazine, sulfamerazine, sulfamethazine and folic acid. 

2. As a strong denaturant in the extraction of total RNA from cells. The guanidine hydrochloride solution can dissolve the protein, cause destruction of the cell structure, destruction of the nucleoprotein structure, and dissociate from the nucleic acid. In addition, the RNase can be inactivated by a reducing agent such as guanidine hydrochloride.